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EC number: 271-085-1
CAS number: 68515-43-5
The influence of Diplast L9 -11 on the fertility and reproductive
capacity of two successive generations was assessed in male and female
rats using methods prescribed by OECD test guidelines. The substance was
administered continuously in the diet at concentrations of 1000, 5000 or
10000 ppm to groups of rats throughout the two generations. The highest
dosage group animals were given 20000 ppm for approximately six weeks
(43 days) at the start of the F0 generation but this was reduced to
10000 ppm because of a marked reduction in bodyweight gain of the males.
The substance had no adverse effects upon fertility or reproductive
performance when rats were exposed to diets containing up to 10000 ppm
of the test material through two successive generations. The substance
had no adverse effect on the seminology parameters investigated and no
histopathological effects on the reproductive organs.
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