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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Flammability

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Administrative data

Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
12 Jan 2021 to 18 Mar 2021
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2021
Report date:
2021

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)
Version / remarks:
2015
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
4-[4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl]-N-[2-methoxy-4-(morpholin-4-yl)-5-nitrophenyl]pyrimidin-2-amine
Cas Number:
1903009-55-1
Molecular formula:
C27H30N8O4
IUPAC Name:
4-[4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl]-N-[2-methoxy-4-(morpholin-4-yl)-5-nitrophenyl]pyrimidin-2-amine
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
Batch (Lot) Number: I20HD2581
Purity: 97.1%
Purity/Composition correction factor: 1.00
Expiry date: 15 August 2022
Physical Description: Yellow powder

STORAGE CONDITIONS
Storage Conditions: At room temperature

Results and discussion

Flammable solids
Key result
Test procedure:
burning rate test: preliminary screening test
Burning time:
1 s

Any other information on results incl. tables

The flame of the gas burner did ignite the test item pile. The test item melted, burned with a yellow/blue flame, emitted yellow sparks and turned into a black residue. White smoke was observed. After removal of the ignition source, the flame extinguished after 2 seconds and no propagation of combustion was observed.

Applicant's summary and conclusion

Interpretation of results:
not classified based on GHS criteria
Conclusions:
The preliminary screening test was performed for the determination of the flammability of JNJ-73848268-AAA (T003903).
No propagation of combustion of the test item along 200 mm length of the pile within 2 minutes was observed. According to the guidelines, performance of the burning rate test is not required. Based on the results obtained, the test item is considered ‘not flammable’.