Registration Dossier
Registration Dossier
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EC number: 206-743-9 | CAS number: 372-09-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Cyanoacetic acid was not mutagenic in the standard Ames assay in bacteria with and without metabolic activation. Neither Salmonella typhimurium TA102 nor E. coli WP2 were tested in these Ames tests, however, this is an acceptable restriction, because it can be assumed that cyanoacetic acid has oxidizing or cross-linking potential, which may be detected by TA102 or E. coli WP2.
There is no structural alert for genotoxicity.
Short description of key information:
SIDS INITIAL ASSESSMENT PROFILE Cyanoacetates - SIAM 23, 17-20 October 2006
Endpoint Conclusion:
Justification for classification or non-classification
From the available information, there is no indication of a genotoxic potential of the substance, both for gene mutations and chromosomal aberrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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