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Diss Factsheets

Physical & Chemical properties

Density

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Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
January 30, 2002
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
Cited as Directive 92/69/EEC, A.3
GLP compliance:
yes (incl. QA statement)
Type of method:
pycnometer method
Key result
Type:
relative density
Density:
0.87 other: dimensionless
Temp.:
20 °C
Temperature: 20.0 - 20.1°C.
relative density at +20°C/+4°C
Assay 1: 0.8643
Assay 2: 0.8709
Conclusion (mean): D(+20°C/+4°C) = 0.868±0.01
Conclusions:
Under the study conditions, the relative density of the test substance was 0.87 at 20°C.

Executive summary:

A study was conducted to determine the relative density of the test substance using a pycnometer according to the OECD Guideline 109 and EU Method A.3, in compliance with GLP. Under the study conditions, the relative density of the test substance was 0.87 at 20°C (Mourgues, 2002).

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From October 15, 2004 to December 22, 2004
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
GLP compliance:
yes (incl. QA statement)
Type of method:
pycnometer method
Key result
Type:
relative density
Density:
0.86 other: dimensionless
Temp.:
20.2 °C
Conclusions:
Under the study conditions, the relative density of the test substance was 0.86 at 20.2°C.
Executive summary:

A study was conducted to determine the relative density of the test substance using a pycnometer according to the EU Method A.3, in compliance with GLP. Under the study conditions, the relative density of the test substance was 0.86 at 20.2°C (White, 2004).

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
August 23, 2007
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
GLP compliance:
yes
Type of method:
pycnometer method
Key result
Type:
relative density
Density:
0.99 other: dimensionless
Temp.:
20

Table 1. Density values

 Measurements Determination    
 
Relative density  0.988  0.988 
Conclusions:
Under the study conditions, the relative density of the test substance was determined to be 0.988 at 20.0 ± 0.5°C.
Executive summary:

A study was conducted to determine the density of the test substance according to EU Method A.3 (pycnometry). The relative density of the test substance was determined to be 0.988 at 20.0 ± 0.5°C (White, 2007).

Description of key information

Determination of the relative density according to:

- OECD Guideline 109 and EU Method A.3 (Mourgues, 2002)

- EU Method A.3 (White, 2004, 2007)

Key value for chemical safety assessment

Relative density at 20C:
0.87

Additional information

- 0.87 at 20.0°C (Mourgues, 2002)

- 0.86 at 20.2°C (White, 2004)

- 0.99 at 20.0 ± 0.5°C (White, 2007)