Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
Not available
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Secondary literature source, rating as per REACH Guidance document 7a. (Endpoint-specific guidance).
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1970

Materials and methods

Study type:
study with volunteers
Endpoint addressed:
repeated dose toxicity: oral
Principles of method if other than guideline:
Method followed unknown, data from handbook.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Glycerides, C8-18 and C18-unsatd.
EC Number:
266-946-3
EC Name:
Glycerides, C8-18 and C18-unsatd.
Cas Number:
67701-28-4
IUPAC Name:
Glycerides, C8-18 and C18-unsatd.
Details on test material:
- Name of test material (as cited in study report): Coconut oil (CAS N° 8001-31-8, EC N° 232-282-8); under the SDA nomenclature, the name of this substance is ‘Glycerides, C8-18 and C18-unsatd.’

Method

Type of population:
general
Subjects:
No information
Ethical approval:
not specified
Route of exposure:
dermal
Reason of exposure:
intentional
Exposure assessment:
not specified

Results and discussion

Clinical signs:
No data

Any other information on results incl. tables

None

Applicant's summary and conclusion

Conclusions:
The test substance is not irritating to human skin.
Executive summary:

According to the Biotech Index, ‘glycerides, C8-18 and C18-unsatd.’ (as coconut oil) is not irritating to human skin after 4 h of exposure.