N-[2-[bis(carboxymethyl)amino]ethyl]-N-(1-oxononyl)Glycine

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2022-01-17 to 2022-04-04

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

1996

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: Knudsen cell

Key result

Test no.:

#1

Temp.:

20 °C

Vapour pressure:

0.004 Pa

Remarks on result:

other: Estimated result < 4.4E-03 Pa

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

0.004 Pa

Remarks on result:

other: Estimated result < 4.4E-03 Pa

Test no.:

#3

Temp.:

50 °C

Vapour pressure:

0.004 Pa

Remarks on result:

other: Estimated result < 4.4E-03 Pa

Thermal stability (DSC)

In the temperature range of 160 – 170 °C a first endothermic effect was observed. In the temperature range of 180 – 220 °C a second endothermic effect was observed. The test was terminated at 300 °C. The results of the DSC measurement are summarized in Table 1.

 

Table 1: Results of the DSC measurement

Measurement	Crucible/atmosphere	Sample weight [mg]	Start [°C]	Energy [J/g]
1	Glass/air	6.03	160 (endothermic) 180 (endothermic)	+10     +200

 

Effusion method: Knudsen cell

The vapour pressure was measured in the temperature range of approx. 15 to 85 °C. The measured vapour pressure values together with the measured temperatures are listed in Table 2.

 

Table 2: Results of the effusion method

No.	Temperature [°C]	Vapour pressure [Pa]
1	14.5	3.4 x 10^-3
2	19.5	4.4 x 10^-3
3	24.5	1.5 x 10^-3
4	29.5	1.9 x 10^-3
5	34.5	1.8 x 10^-3
6	39.4	1.1 x 10^-3
7	44.5	4.3 x 10^-3
8	54.5	4.3 x 10^-3
9	64.4	2.8 x 10^-3
10	74.4	1.4 x 10^-3
11	84.4	7.8 x 10^-4

 

Due to the fact that the test item showed no proper linear correlation of the vapour pressure against the inverse temperature 1/T, the Antoine constants could not be evaluated in the measured temperature range. Therefore, the vapour pressure was estimated according to the measured vapour pressures.

The test item showed no evaluable vapour pressure curve in the temperature range of 15 to 85 °C. Due to this result, the vapour pressures for the temperatures 20, 25 and 50 °C are estimated on the basis of the maximum measured vapour pressures (Table 3).

 

Table 3: Calculated vapour pressures

Temperature [°C]	Vapour pressure [Pa]
20	< 4.4 x 10^-3
25	< 4.4 x 10^-3
50	< 4.4 x 10^-3

Conclusions:

The vapour pressure of the test item was estimated to be:
20 °C: < 4.4E-03 Pa
25 °C: < 4.4E-03 Pa
50 °C: < 4.4 E-03 Pa

Executive summary:

In an experimental GLP study according to EU Method A.4. and OECD Test Guideline 104, the vapour pressure of the test item was estimated for the temperatures 20, 25 and 50 °C to be

20 °C: < 4.4E-03 Pa

25 °C: < 4.4E-03 Pa

50 °C: < 4.4 E-03 Pa

Description of key information

In an experimental GLP study according to EU Method A.4. and OECD Test Guideline 104, the vapour pressure of the test item was estimated for the temperatures 20, 25 and 50 °C to be

20 °C: < 4.4E-03 Pa

25 °C: < 4.4E-03 Pa

50 °C: < 4.4 E-03 Pa

Key value for chemical safety assessment

Vapour pressure:

0.004 Pa

at the temperature of:

20 °C

Additional information

No linear vapour pressure curve in the temperature range of 15 to 85 °C determined, therfore the maximum measured vapour pressures are considere.

Estimated vapour pressure < 0.0044 Pa