N-[2-[bis(carboxymethyl)amino]ethyl]-N-(1-oxononyl)Glycine

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2022-01-17 to 2022-04-04

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Version / remarks:

1996

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Decomposition:

yes

Decomp. temp.:

> 183.7 °C

Results of the DSC measurements are summarised in Table 1.

Table 1: Results of the DSC measurements

Measurement	Sample weight [mg]	Onset of effect [°C]	Range of effect [°C]	Weight loss [mg]	Atmospheric pressure [hPa]
1	8.28	163.45 183.67 -	160-170 (endo) 180-240 (endo) 290-350 (exo)	7.05	1022.8
2	7.93	163.46 183.71	160-170 (endo) 180-240 (endo) 290-350 (exo)	6.70	1021.7

The test item showed a first small endothermic effect in the temperature range of 160 – 170 °C and a second larger endothermic effect in the temperature range of 180 – 240 °C. An exothermic effect was detected in the temperature range of 290 – 350 °C. No further thermal effects were observed up to the test end temperature of 500 °C.
During the verification measurements with the capillary method it was observed that the test item started to melt at approx. 180 °C. During the melting process the formation of gas bubbles (foaming) was observed. At 200 °C the test item was completely molten and had turned into a clear yellow liquid. 

The test item did not show a separate distinct endothermic signal which could be assigned to the boiling of the test item above the melting temperature of the test item. Nevertheless, gas formation directly following the melting process was observed by capillary method. However, the cause for the formation of gas can be based on a decomposition process of the test item instead of boiling. If the test item had been boiling the weight loss at the end of the DSC measurement would have been approx. 100 % instead of only approx. 85 %. This means that decomposition product probably remained as residue in the crucible. Furthermore, the liquid in the capillary had turned yellow at 200 °C. This indicates a chemical reaction at these temperatures.

The melting process is directly followed by a decomposition process accompanied by gas evolution. As the test item starts to decompose before reaching its boiling point, the boiling temperature can not be specified.

Conclusions:

The boiling point of the test item can not be defined as it starts to decompose during the melting process.

Executive summary:

The boiling point of the test item can not be defined as it starts to decompose during the melting process. The results were obtained by DSC and optically confirmed by capillary method according to EU Method A.2. and OECD Test Guideline 103 in a GLP study.

Description of key information

The boiling point of the test item can not be defined as it starts to decompose during the melting process. The results were obtained by DSC and optically confirmed by capillary method according to EU Method A.2. and OECD Test Guideline 103 in a GLP study.

Key value for chemical safety assessment

Temperature of decomposition (state purity):

200 °C

Additional information

Temperature of decomposition around 200°C.

HPLC purity 100 %