Registration Dossier
Registration Dossier
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EC number: 226-552-4 | CAS number: 5423-23-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-09-24 - 2018-10-08
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 27 July 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 19 March 2014
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Version / remarks:
- March 1998
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- >= 200 - <= 250 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 200 g/L
- Incubation duration:
- 10 min
- Remarks on result:
- other: see 'Remarks'
- Remarks:
- no pH stated in the report, temperature is stated as room temperature
- Details on results:
- Tthe water solubility of test item was determined to be in the range between 200 and 250 g/L at room temperature based on this simplified test (OECD 105).
- Conclusions:
- Tthe water solubility of test item was determined to be in the range between 200 and 250 g/L at room temperature based on this simplified test (OECD 105).
- Executive summary:
As a very high water solubility of the test item (a salt) is expected the water solubility the sample was determined by means of a simplified test (OECD 105). This is also in accordance with EU Method A.6 and OPPTS 830.7840. Study was performed based on GLP-principles.
Based on this test, a water solublity in the range between 200 and 250 g/L at room temperature can be deduced.
Reference
Description of key information
As a very high water solubility of the test item (a salt) is expected the water solubility of the sample was determined by means of a simplified test (OECD 105). This is also in accordance with EU Method A.6 and OPPTS 830.7840. Study was performed based on GLP-principles.
Based on this test, a water solublity in the range between 200 and 250 g/L at room temperature can be deduced.
Key value for chemical safety assessment
- Water solubility:
- 250 g/L
- at the temperature of:
- 20 °C
Additional information
In the report is only stated at 'room temperature', therefore it is assumed that a temperature of 20 °C is applicable for the CSA. Also a range for water solubility is given due to the high water solubility a simplified test was conducted. Therefore the higher value of the range is choosen for the CSA as worst case value, because this value reflects more the availability of the subtance in aqueous phase.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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