Registration Dossier
Registration Dossier
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EC number: 224-388-8 | CAS number: 4337-75-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2005-07-05 - 2005-08-04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Read-Across Study
- Justification for type of information:
- This study for the source substance SMCT is used as read-across to the registered (target) substance SMLT. See section 13 for the full read-across justification.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum for municipal STP Taunusstein-Bleidenstadt, washed twice with mineral nutirent
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 91.5 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- Temperature maintained between 20.0-21.7 deg C (mena 20.8 deg C)
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 82
- Sampling time:
- 28 d
- Remarks on result:
- other: mean of two runs
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 61
- Sampling time:
- 12 d
- Details on results:
- SMCT is a UVCB and therefore the 10d Window criteria is not applicable.
- Results with reference substance:
- Sodium benzoate was degraded 97% after 28d, the 10d window was met after 5d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The source substance sodium methyl cocoyl taurate (SMCT) was tested in an OECD 301B CO2 Evolution test and was found to be readily biodegradable. Therefore, the registration (target) substance SMLT is also considered readily biodegradable on the basis of read-across (see read-across justification document in Section 13).
- Executive summary:
The source substance sodium methyl cocoyl taurate (SMCT) was tested in an OECD 301B CO2 Evolution test and was found to be readily biodegradable, achieving 82% degradation after 28d (mean of 2 runs).
Therefore, the registration (target) substance SMLT is also considered readily biodegradable on the basis of read-across (see read-across justification document in Section 13).
Reference
Description of key information
The source substance sodium methyl cocoyl taurate (SMCT) was tested in an OECD 301B CO2 Evolution test and was found to be readily biodegradable. Therefore, the registration (target) substance SMLT is also considered readily biodegradable on the basis of read-across (see read-across justification document in Section 13).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
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