Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 607-240-0 | CAS number: 23511-73-1
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22 December 2008 to 17 February 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Food and Consumer Product Safety Authority, Den Haag, Netherlands
- Type of method:
- effusion method: by loss of weight or by trapping vaporisate
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0.004 Pa
- Remarks on result:
- other: extrapolated value
Reference
The linear regression analysis of the reference substances’ log VT,20(determined in this study) and log PT,20(from literature) using the least squares method yielded the following equation of the vapour pressure regression curve:
log PT,20= 1.07 x log VT,20+ 4.52 (r = 0.996, n = 10)
The results of the isothermal TGA analysis are reported in the following table.
Temperature (°C) |
Weight loss (µg/min) |
VT(g/cm²/h) |
log VT |
100 |
6.817 |
8.14 x 10-4 |
-3.09 |
8.317 |
9.93 x 10-4 |
-3.00 |
|
110 |
16.58 |
1.98 x 10-3 |
-2.70 |
17.70 |
2.11 x 10-3 |
-2.68 |
|
120 |
33.80 |
4.03 x 10-3 |
-2.39 |
34.97 |
4.17 x 10-3 |
-2.38 |
|
130 |
64.49 |
7.70 x 10-3 |
-2.11 |
67.00 |
8.00 x 10-3 |
-2.10 |
The coefficient of correlation (r) related to the the plot of the logVTof the test substance as function of the reciprocal temperatures was > 0.99. Extrapolation of the curve to 20 °C resulted in a value of -6.48 for the logVT,20of the test substance. Fitting this value in the regression curve, a vapour pressure of 3.89 x 10-3Pa (2.92 x 10-5) mm Hg was obtained.
Conclusion
The vapour pressure of the test substance at 20°C (293K) was 3.89 x 10-3Pa according to OECD Guideline 104.
Description of key information
3.89E-03 Pa at 20 °C (OECD Guideline 104, vapour pressure curve)
Key value for chemical safety assessment
- Vapour pressure:
- 0.004 Pa
- at the temperature of:
- 20 °C
Additional information
The vapour pressure curve used to derive the key value (at 20 °C) was determined using experimental values determined by effusion method.
As supporting information, a QSAR calculation performed with SPARC software v 4.5 resulted in a vapour pressure of 1.72E-03 Pa, which is of the same order of magnitude of the experimentally determined value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
