4-ethoxy-2,3-difluoro-4'-propyl-1,1'-biphenyl

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2011-04-06 to 2011-04-07

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

348.1 - 351.4 °C

Atm. press.:

1 013.3 hPa

Decomposition:

no

Three measurements in aluminium crucibles with a hole showed an endothermic effect (boiling) in the temperature range 300 °C to 365 °C with an onset temperature between 348.4 °C and 351.6 °C. The onset temperature is derived from the intersection of the tangent line with the highest slope of the endothermic peak with the baseline.

ldent-No.	Onset / °C	Temperature range / °C	Crucible
31691	351.04	330 - 365	Aluminium with a hole
31692	348.38	300 - 365	Aluminium with a hole
31693	351.61	330 - 365	Aluminium with a hole

 

For the correction Δt of the boiling point to standard atmospheric pressure (1013.3 hPa) the equation, table and graphs of H.B. Hass and R.F. Newton in „CRC Handbook of Chemistry and Physics, 74th ed. 1993-1994", pages 15-16 and 15-17 were used.

Δt = [(273.15+t) (3.0057-log p)] / [Φ+ 0.15(3.0057-log p)]             (t in °C, p in hPa)

For the estimation of Φthe test item was classified in group 2 (ethers) according to the table of

H.B Hass and R.F. Newton.

ldent.-No.	Onset / °C	Atmospheric pressure / hPa	Φ(group 2)	Δt / °C	Boiling point at 1013.3 hPa / °C
31691	351.04	1018	5.269	-0.243	350.80
31692	348.38	1018	5.264	-0.242	348.14
31693	351.61	1018	5.271	-0.243	351.37

The test item had a boiling range at atmospheric pressure (1013.3 hPa) of 348.1 °C to 351.4 °C.

Conclusions:

The boiling range of the test item at atmospheric pressure (1013.3 hPa) was determined to be 348.1 °C to 351.4 °C.

Executive summary:

A study was conducted according to OECD test guideline 103 and Regulation (EC) No 440/2008 method A.2 to determine the boiling point of the test item using differential scanning calorimetry (DSC 25 -400 °C). The test item and the reference are heated up from the starting temperature to the final temperature at a constant heating rate in a defined atmosphere (nitrogen). Open crucibles are used as containers for the test item and as empty reference crucible. The quantity of heat absorbed or released is measured and recorded. No decomposition was observed. The test item had a boiling range at atmospheric pressure (1013.3 hPa) of 348.1 °C to 351.4 °C.

Description of key information

The boiling range of the test item at atmospheric pressure (1013.3 hPa) was determined to be 348.1 °C to 351.4 °C.

Additional information

A study was conducted according to OECD test guideline 103 and Regulation (EC) No 440/2008 method A.2 to determine the boiling point of the test item using differential scanning calorimetry (DSC 25 -400 °C). The test item and the reference are heated up from the starting temperature to the final temperature at a constant heating rate in a defined atmosphere (nitrogen). Open crucibles are used as containers for the test item and as empty reference crucible. The quantity of heat absorbed or released is measured and recorded. No decomposition was observed. The test item had a boiling range at atmospheric pressure (1013.3 hPa) of 348.1 °C to 351.4 °C.