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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1971

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No data on methods.
GLP compliance:
not specified
Test type:
other: not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-pyridylamine
EC Number:
207-988-4
EC Name:
2-pyridylamine
Cas Number:
504-29-0
Molecular formula:
C5H6N2
IUPAC Name:
pyridin-2-amine
Specific details on test material used for the study:
- Name of test material: 2-aminopyridine
- state: powder.

Test animals

Species:
other: human
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Analytical verification of test atmosphere concentrations:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
other: TCLo
Effect level:
0.5 ppm
Based on:
test mat.
Remarks on result:
other: inhalation, human

Applicant's summary and conclusion

Interpretation of results:
Category 3 based on GHS criteria
Remarks:
EU criteria
Conclusions:
According to handbook data, the test item is highly toxic by ingestion and inhalation. Tolerance: 0.5ppm.
Executive summary:

According to 'The condensed chemical dictionary', 8th edition (peer reviewed handbook data), the test item is highly toxic by ingestion and inhalation. Tolerance: 0.5ppm.