Registration Dossier
Registration Dossier
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EC number: 203-870-1 | CAS number: 111-44-4
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Toxicometri parameters of industrial chemicals under single exposure
- Author:
- Izmerov, N.F., Sanotsky, I.V. & Sidorov, K.K.
- Year:
- 1 982
- Bibliographic source:
- UNEP, Centre of International Projects, GKHT, Moscow, p 45.
Materials and methods
- Endpoint addressed:
- respiratory irritation
Test material
- Reference substance name:
- Bis(2-chloroethyl) ether
- EC Number:
- 203-870-1
- EC Name:
- Bis(2-chloroethyl) ether
- Cas Number:
- 111-44-4
- Molecular formula:
- C4H8Cl2O
- IUPAC Name:
- 1-chloro-2-(2-chloroethoxy)ethane
- Test material form:
- liquid
Constituent 1
Method
- Ethical approval:
- not specified
- Exposure assessment:
- not specified
Results and discussion
- Results:
- Based on subjective sensations of volunteers, the LOEL was 0.019 mg/L following a 2 min exposure period.
Applicant's summary and conclusion
- Executive summary:
This data book originally published by the USSR State Committee for Science and Technology and republished in English by UNEP. As the data originate from leading international organizations, they are judged reliable. Based on subjective sensations of volunteers, the LOEL was 0.019 mg/L following a 2 min exposure period.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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