Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

Currently viewing:

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
other: Summary report
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: only result given

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methylthiazolidine-2-thione
EC Number:
217-614-1
EC Name:
3-methylthiazolidine-2-thione
Cas Number:
1908-87-8
Molecular formula:
C4H7NS2
IUPAC Name:
3-methyl-1,3-thiazolidine-2-thione
Test material form:
not specified
Details on test material:
- Name of test material (as cited in study report): 3-Methyl-2-thiazolidinthion

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
other: classification result
Remarks on result:
other: slightly irritating
Irritant / corrosive response data:
slightly irritating to the eye

Applicant's summary and conclusion

Interpretation of results:
slightly irritating
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
Given data are not sufficient to assess the reliability of the information, but the result supports the information given in the two WoE studies, i.e. that the substance has minor irritating properties which are not sufficient for classification as irritating under the EU CLP Regulation.
Executive summary:

3-Methyl-thiazolidin-2-thion is slightly irritating to the rabbit eye.