Registration Dossier
Registration Dossier
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EC number: 244-966-3 | CAS number: 22412-97-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Information is based on results of testing of an analogue and of a substance belonging to an analogue category. The key value refers to the maximum loading tested.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
The microbial toxicity of tetradecyl laurate is based on an oxygen-consumption study with the analogue tetradecyl myristate (CAS 3234-85-3) conducted according to OECD 301C under GLP conditions (Ministry of Economy, Trade and Industry, Japan, 1992). A test concentration of 100 mg/L (nominal) did not inhibit the biodegradation process of the test substance. Therefore, the test substance is not toxic to activated sludge microorganisms and the test concentration can be used as a NOEC value for the toxicity to activated sludge microorganisms. Thus, a NOEC (28 d) of ≥ 100 mg/L resulted.
An additional study with the read-across substance Fatty acids, C8 - 10, C12 - 18-alkyl esters (CAS 95912-86-0) was performed according to OECD 209 under GLP conditions (Hammer, 2013). Sludge microorganisms were exposed to the test substance up to a nominal concentration of 1000 mg/L. No effects were observed based on the respiration rate after 3 h of incubation resulting in an EC10 (3 h) of > 1000 mg/L. Instead, an increase of respiration was recorded in all treatments compared to the control values. In conclusion the toxicity to activated sludge microorganisms is assumed to be low and instead the presence of the fatty acid esters stimulated microbial acitivity.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
