Registration Dossier
Registration Dossier
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EC number: 248-324-3 | CAS number: 27206-35-5
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Hydrolysis: hydrolytically stable, -1% - 1.1% in 5 days at 50°C (OECD 111, EU method C.7, GLP)
Key value for chemical safety assessment
Additional information
There is one OECD 111 / EU method C.7 study under GLP on the hydrolysis of Bis-(sodium sulfopropyl)-disulfide available, assessed with Klimisch 1 and hence considered as sufficiently reliable to cover this endpoint.
Tier 1 testing revealed that, after five days at 50°C, the concentrations of the test item lay above 90 % of the nominal start concentration at all three pH values, therefore tier 2 did not have to be conducted. The test item is considered as hydrolytically stable.
There is no reason to believe that this result is not reliable, and consequently, there is no data gap identified. For further risk assessment, hydrolytical degradation of the substance is not an issue, however, biotic degradation / metabolism still needs to be regarded.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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