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EC number: 810-760-2 | CAS number: 149855-64-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In a 48-hour acute toxicity study, neonate Daphnia magna were exposed to 2-Propylheptyl methacrylate in accordance with the OECD 202 guideline. The LC50 was > 0.153 mg/L.
Key value for chemical safety assessment
Additional information
In a 48-hour acute toxicity study, neonate Daphnia magna were exposed to 2-Propylheptyl methacrylate at measured concentrations of 0 (control), 0.153 mg/L under daily-renewal conditions in accordance with the OECD 202 guideline. The water pH, temperature and dissolved oxygen were within acceptable guideline specifications. Immobilization (mortality) and sublethal effects were observed daily. The 48 hour EC50values determined in this acute toxicity study were: >100 mg/L based on the nominal concentration of the test substance and >0.153 mg/L based on the mean measured concentrations. The measured concentration in freshly prepared saturated solution was 0.175 - 0.18 mg/L and after 24-h exposure concentrations were 0.12 -0.135 mg/L. The ratio of the highest concentration to the lowest concentration did not exceed 1.5:1, so the goal for limiting variability of measurements from the same treatment level was achieved. Consequently, the mean measured concentration is an accurate representation of exposure level maintained throughout the test period.
The toxicity results presented here are consistent with the results from preliminary tests. The following effect concentraton (mg/L) was obtained after 48 hours based on mean measured concentrations EC50 > 0.153 mg/L.T
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