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EC number: 258-904-8
CAS number: 53988-10-6
Biodegradation in water (screening test): ready biodegradability
The test was conducted under GLP according to OECD TG 301 C. Within 28
days, a degradation rate of 0 % was determined. Therefore, the test
substance is 'Not Readily Biogradable'. The reference compound aniline
shohed 74 % degradation after 14 days.
Biodegradation in water and sediment (simulation test)
ZMB2 dissociates to MB2 and zinc ions within seconds when a non-aqueous
solution of ZMB2 is exposed to an aqueous environment.
Therefore, a read-across approach (structural analogue or surrogate)
from Vulkanox ZMB2 (1,3-dihydro-4(or
5)-methyl-2H-benzimidazole-2-thione, zinc salt; CAS 61617-00-3) to
Vulkanox MB2 (1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2- thione, CAS
53988-10-6) was conducted for this endpoint.
This study is concerned with the aerobic mineralisation of ZMB2 in
natural surface water under controlled laboratory conditions. It was
carried out according to the OECD Guideline 309 "Aerobic Mineralisation
in Surface Water – Simulation Biodegradation Test”. The incubation was
performed using a 14C-labelled test item [phenyl-U-14C]zinc-4- and
5-methyl-2-mercaptobenzimidazole under aerobic conditions at 12 °C in
the dark. The DegT50 value of MB2 (12° C) is 12.9 days (low
concentration) and 24.6 days (high concentration).
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