Registration Dossier
Registration Dossier
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EC number: 209-008-0 | CAS number: 552-30-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Acute toxicity to fish: LC50 = > 792 mg/L; NOEC = 792 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 792 mg/L
Additional information
One reliable study addresses the short-term toxicity of trimellitic anhydride to freshwater invertebrates. In this study (Knacker et al., 1992) TMA was first treated with aqueous NaOH solution, to convert the acid anhydride to the sodium salt(s) of TMLA, and exposure in this study was consequently to sodium trimellitate (following neutralisation of excess alkali).
No toxicity was observed under these conditions: D. magna 48 hour LC50 (static): >792 mg TMA-equiv/L, 96 hour NOEC: 792 mg TMA-equiv/L; These endpoints are mean measured values and represent the highest concentration applied.
Trimellitic anhydride and the more environmentally relevant trimellitic acid (its hydrolysis product) exhibit very low short-term toxicity to aquatic invertebrates.
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