Registration Dossier
Registration Dossier
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EC number: 206-114-9 | CAS number: 302-01-2
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: secondary literature
Data source
Reference
- Reference Type:
- secondary source
- Title:
- personal communication, cited in: Krop S (1954). Toxicology of hydrazine, a review.
- Author:
- Horton RG and Conn LW
- Year:
- 1 954
- Bibliographic source:
- Arch. Ind. Hyg. Occup. Med. 9, 199-204.
Materials and methods
- Principles of method if other than guideline:
- No further data given.
- GLP compliance:
- no
- Test type:
- other: no data: secondary citation
Test material
- Reference substance name:
- Hydrazine
- EC Number:
- 206-114-9
- EC Name:
- Hydrazine
- Cas Number:
- 302-01-2
- Molecular formula:
- H4N2
- IUPAC Name:
- hydrazine
- Details on test material:
- IUCLID4 Test substance: no data
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- other: no data: secondary citation
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- no data: secondary citation
Administration / exposure
- Type of coverage:
- other: no data: secondary citation
- Vehicle:
- other: no data: secondary citation
- Details on dermal exposure:
- no data: secondary citation
- Duration of exposure:
- no data: secondary citation
- Doses:
- no data: secondary citation
- No. of animals per sex per dose:
- no data: secondary citation
- Control animals:
- other: no data: secondary citation
- Details on study design:
- no data: secondary citation
- Statistics:
- no data: secondary citation
Results and discussion
- Preliminary study:
- no data: secondary citation
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- 91 mg/kg bw
- Mortality:
- no data: secondary citation
- Clinical signs:
- other: no data: secondary citation
- Gross pathology:
- no data: secondary citation
- Other findings:
- no data: secondary citation
Any other information on results incl. tables
No data: secondary citation.
Applicant's summary and conclusion
- Executive summary:
Using hyrazine the LD50 (dermal, rat) is reported to be 91 mg/kg bw (Horton 1954 cited by Krop 1954).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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