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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1974
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
other: Standard Methods for the Examination of Water and Wastewater, 13th Edition, 1971
GLP compliance:
not specified
Analytical monitoring:
no
Vehicle:
no
Details on test solutions:
PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: The test substance was directly added to the dilution water.
Test organisms (species):
Pimephales promelas
Details on test organisms:
TEST ORGANISM
- Common name: fathead minnow
- Source: Obtained from commercial suppliers.
- Length at study initiation: 2.5 - 5.0 cm
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Hardness:
30 - 60 mg/L
Test temperature:
71 - 76 °F (21.6 - 24.4 °C)
pH:
7.1 (initial)
Dissolved oxygen:
7.5 - 9.0 mg/L
Details on test conditions:
TEST SYSTEM
- Test vessel:
- Fill volume: 18.5 L
- Aeration: yes
- No. of organisms per vessel: 10

EFFECT PARAMETERS MEASURED: mortality

TEST CONCENTRATIONS
- Range finding study
- Test concentrations: Concentrations ranging from 10 - 10000 mg/L to identify definite test concentrations.
Reference substance (positive control):
not specified
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
125 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
110 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
110 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Description of key information

LC50 (96 h): 110 mg/L for Pimephales promelas (Standard Methods for the Examination of Water and Wastewater (13th Edition, 1971))

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Dose descriptor:
LC50
Effect concentration:
110 mg/L

Additional information

One study investigating the short-term toxicity of 2-(2-ethoxyethoxy)ethyl acetate (CAS 112-15-2) to fish is available (Waggy & Payne, 1974). The study was performed according to the Standard Methods for the Examination of Water and Wastewater (13th Edition, 1971) under non-GLP conditions. Pimephales promelas was exposed to concentrations of 10 - 10000 mg/L (nominal). After the exposure of 96 h an LC50 of 110 mg/L was calculated.