Registration Dossier
Registration Dossier
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EC number: 232-164-6 | CAS number: 7789-41-5
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Study period:
- 2007
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
- Objective of study:
- toxicokinetics
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- other
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Sodium bromide
- EC Number:
- 231-599-9
- EC Name:
- Sodium bromide
- Cas Number:
- 7647-15-6
- IUPAC Name:
- sodium bromide
- Details on test material:
- Bromide ions
Constituent 1
- Radiolabelling:
- not specified
Results and discussion
Toxicokinetic / pharmacokinetic studies
Toxicokinetic parameters
- Toxicokinetic parameters:
- other: The biological half life of Bromide is 8-13 days
Applicant's summary and conclusion
- Conclusions:
- The weight of evidence collected in both man and laboratory animals does suggest that sufficient data is already available without the need for additional testing. The target organs, i.e. endocrine and neural systems, have been identified and significant data for the kinetics of bromide are available.
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