Registration Dossier
Registration Dossier
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EC number: 455-040-5 | CAS number: 3789-59-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 July - 7 Aug 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- GLP compliance:
- yes
- Test type:
- acute toxic class method
- Limit test:
- no
Test material
- Details on test material:
- - Name of test material: (S)-1-Phenylpropylamine (CAS 3789-59-1)
Constituent 1
Test animals
- Species:
- rat
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Doses:
- 200, 2000 mg/kg
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 200 - 2 000 mg/kg bw
Applicant's summary and conclusion
- Conclusions:
- The oral LD50 in rats was determined to range between 200 mg/kg bw and 2000 mg/kg bw.
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