Registration Dossier
Registration Dossier
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EC number: 241-866-1 | CAS number: 17927-72-9
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- in vivo
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 14024-63-6
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-Commercial
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- Skin sensitisation. Multicase model A33.
- GLP compliance:
- not specified
- Type of study:
- other: GPMT or human experience
Test material
- Reference substance name:
- Bis(pentane-2,4-dionato-O,O')zinc
- EC Number:
- 237-860-3
- EC Name:
- Bis(pentane-2,4-dionato-O,O')zinc
- Cas Number:
- 14024-63-6
- IUPAC Name:
- zinc bis(4-oxopent-2-en-2-olate)
Constituent 1
In vivo test system
Test animals
- Species:
- other: Guinea pig or human
- Strain:
- not specified
- Sex:
- not specified
Study design: in vivo (non-LLNA)
Induction
- Route:
- other: no data
- Vehicle:
- no data
Challenge
- Route:
- other: no data
- Vehicle:
- no data
Study design: in vivo (LLNA)
- Vehicle:
- unchanged (no vehicle)
Results and discussion
In vivo (non-LLNA)
Results
- Reading:
- 1st reading
- Group:
- test chemical
- No. with + reactions:
- 0
- Clinical observations:
- Non sensitising
- Remarks on result:
- other: Reading: 1st reading. Group: test group. No with. + reactions: 0.0. Clinical observations: Non sensitising.
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Skin sensitization of bis(pentane-2,4-dionato-O,O')zinc is estimated as negative.
- Executive summary:
Skin sensitization of bis(pentane-2,4-dionato-O,O')zinc is estimated as negative.
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