Registration Dossier
Registration Dossier
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EC number: 212-201-2 | CAS number: 768-94-5
Flammability
Administrative data
Link to relevant study record(s)
Description of key information
The mixture (amantadine in xylene) is flammable upon ignition
The pure substance and the mixture has no pyrophoric properties and does not liberate flammable gases on contact with water.
The substance and the mixture are not a self-reactive.
The substance and the mixture are not organic peroxides.
The substance as a solution in xylene is not a self-heating substance or mixture.
Key value for chemical safety assessment
- Flammability:
- flammable
Additional information
The mixture (amantadine in xylene) is flammable (derived from flash point).
Based on chemical structure for the pure substance and the mixture pyrophoric properties and flammability in contact with water are not to be expected.
The mixture (amantadine in xylene) does not need to be classified as self-reactive as the heat of decomposition is less than 300 J/g.
The pure substance (amantadine) does not need to be classified as self-reactive as there are no chemical groups present in the molecule associated with explosive or self reactive properties.
The mixture (amantadine in xylene) does not need to be classified as self-heating as the substance is a liquid.
The pure substance and the mixture does not need to be classified as an organic peroxide as by definition based on their chemical structure the substance is no organic peroxide.
Justification for classification or non-classification
Amantadine:
Based on the chemical structure and taking into account the provisions laid down in Directive 67/548/EEC, as amended for the 31st time in Directive 2009/2/EG, the substance is not considered to be classified as flammable in contact with water or pyrophoric.
Based on the chemical structure and taking into account the provisions laid down in Regulation (EC) No 1272/2008, as amended for the sixth time in Regulation (EC) No 605/2014., the substance is not considered to be classified as flammable in contact with water, pyrophoric, self-reactive substance, or organic peroxide.
Amantadine in Xylene
The following classification criteria for the slution in xylene are met:
R10 (flammable) of EU Directive 67/548/EEC: flash point >= 21 °C and <= 55 °C;
Flammable liquids, Category 3 (flammable liquids and vapour) of EU CLP: flash point >= 23 °C and <= 60 °C
Based on the chemical structure and taking into account the provisions laid down in Directive 67/548/EEC, as amended for the 31st time in Directive 2009/2/EG, the substance is not considered to be classified as flammable in contact with water or pyrophoric.
Based on the chemical structure and taking into account the provisions laid down in Regulation (EC) No 1272/2008, as amended for the sixth time in Regulation (EC) No 605/2014., the substance is not considered to be classified as flammable in contact with water, pyrophoric, self-reactive substance, self heating substance or organic peroxide.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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