Registration Dossier
Registration Dossier
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EC number: 216-319-5 | CAS number: 1558-33-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Reliable read-across data showed a EC50 (48h) =34.3 mg/L in a daphnia toxicity study.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 34.3 mg/L
Additional information
No reliable data is available for Dichlor(chloromethyl)methylsilane (CAS No. 1558-33-4). The available daphnia study was assinged to Klimsch category 3 due to major procedural deficiencies. However, due to fast hydrolysis read across to the hydrolysis product (Chloromethyl)methylsilandiol is warranted according to ECHA guidance that states that “for substances where hydrolytic DT50is less than 12 hours, environmental effects are likely to be attributed to the hydrolysis product rather than to the parent itself."
Hydrochloric acid is not classified for environmental hazards. Data relevant for the assessment of the other hydrolysis product (Chloromethyl)methylsilandiol can be taken from a daphnia test with (Chloromethyl)dimethoxymethylsilane (CAS# 2212-11-5) which shares the same silanol hydrolysis product by fast hydrolysis. The hydrolysis half-life of (Chloromethyl)dimethoxymethylsilane has been calculated by a validated QRMF (P.R. Fisk 2014) to be 0.5 hours.
The other hydrolysis product (methanol) is not classified for environmental hazards and thus not relevant for the assessment.
For (Chloromethyl)dimethoxymethylsilane a reliable daphnia test is available with a EC50 (48h) = 34.3 mg/L.
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