Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Under experimental conditions Sepisol Fast Violet 2B has been found to be highly irritating for the eyes (with irreversible damage) and is also 
expected to be a respiratory irritant.
Sepisol Fast Violet 2B was not found to be an irritant for the skin of rabbits.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Effects on eye irritation: highly irritating

Effects on respiratory irritation: irritating

Justification for classification or non-classification

The substance Sepisol fast Violet 2B is a powder exhibiting a fine granulometry.

The size of 95.6 % of the total sample is less than 125 µm and most probably the MMAD is below 100 µm.

The particles size distribution has been determined by laser diffraction. 90% of the particles size stands below 220.7 µm; 50% below 60.1 µm and 10% below 10.3 µm. MMAD is expected to be less than 100 µm

It is then expected that this powder will be present all along the respiratory tract and will penetrate deeply in the lungs.

Following a in vivo assay, the substance of concern has been classified as irritant category 1 for the eyes according to the CLP regulation. The effect did not seem to be caused by a mechanical irritation. As a result of the previous reasons Sepisol fast Violet 2B is foreseen to be a possible irritant for the mucous membrane lining the respiratory tract. Therefore it has been classified accordingly: STOT cat 3 - inhalation; H 335.