Registration Dossier
Registration Dossier
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EC number: 700-527-2 | CAS number: 1271488-66-4
Endpoint summary
Administrative data
Description of key information
The skin corrosion and skin irritation potential of the test substance were assessed by in-vitro tests on a human epidermis model (EPISKIN). The eye irritation potential was assessed by using the bovine corneal opacity and permeability test.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Justification for classification or non-classification
The result of the study of in-vitro skin corrosion based on MTT reduction (formazan formation) is that the test substance is not corrosive to skin. Hence the substance does not need to be classified as skin corrosive. The in-vitro skin irritation test also based on MTT reduction does show skin irritancy.
The BCOP in-vitro study on eye irritancy showed that the test substance is not an eye irritant.
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