Registration Dossier
Registration Dossier
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EC number: 215-951-9 | CAS number: 1459-93-4
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.014 mg/L
- Assessment factor:
- 1 000
- PNEC freshwater (intermittent releases):
- 0.14 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.001 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.18 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.018 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The acute aquatic toxicity tests are adequate for the evaluation of the environmental toxicity of the substance (dimethyl isophthalate). The substance is not persistent in the environment, as it exhibits ready biodegradability (as detailed in Section 5.2.1 of this dossier). The substance does not adhere strongly to soil or sediments, as the predicted adsorption coefficient of 90.26 is substantially below the threshold of concern of Koc ≥ 1000 (as detailed in Section 5.4.1 of this dossier). The substance does not exhibit a potential to bioaccumulate, as the partition coefficient of log Kow of 2.10 is substantially below a threshold of concern of log Kow ≥ 3 (as detailed in Section 5.3.1 of this dossier). Although the substance is structurally a phthalate ester (a group of chemicals which contain a structural alert for potential endocrine disruption effects), there is no information indicating that the substance acts as an endocrine disruptor; the substance was determined to be a non-estrogenic xenobiotic in a screening assay (as detailed in Section 6.6 and Section 7.9.3 of this dossier).
Conclusion on classification
According to DSD (Directive 67/548/EEC) this substance is not classified with respect to environmental effects.
According to Regulation (EC) No 1272/2008 this substance is not classified with respect to environmental hazards.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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