ethyl 5,5-diphenyl-2-isoxazoline-3-carboxylate

Explosiveness

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

explosive properties of explosives

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.14 (Explosive properties)

Deviations:

no

GLP compliance:

yes

Parameter:

thermal sensitivity - Koenen test: limiting diameter (mm)

Remarks on result:

not thermal sensitive if heated under defined confinement

Parameter:

sensitiveness to impact: impact energy (J)

Remarks on result:

not sensitive to impact using an impact energy of 40 J

Parameter:

sensitiveness to friction: friction load (N)

Remarks on result:

not sensitive to friction using a friction load of 360 N

Screening test DSC

 

The measurement shows an endothermic effect (melting, 84.5 °C) and a decomposition of the test substance in the range 290-440 °C, with a decomposition energy of 610 J/g. So the test for explosive properties has to be performed.

 

Three tests were performed with a circular nozzle plate with a hole of 2 mm diameter used.

 

Test No.	weight of test substance (g)	nozzle width (mm)	t1 (s)	t2 (s)	reaction	appearance; number of fragments
1	13.80	2.0	47	>300	flame	tube unchanged
2	13.78	2.0	47	>300	flame	tube unchanged
3	13.84	2.0	48	>300	flame	tube unchanged

 

Mechanical sensitivity (shock)

No reaction within 6 tests using a 10 kilogram mass from a height 0.4 m was observed.

 

Mechanical sensitivity (friction)

No reaction within 6 tests pinload with 360 newton was observed.

 

Final result

The heat of decomposition was determined to be above 500 J/g. Therefore the test on explosion properties was performed.

The test substance has no danger of explosion according to the explosive properties in the

sense of Guideline 92/69/EEC, A.14.

Reference 2

Endpoint:

explosive properties of explosives

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance contains chemical groups associated with explosive properties which include oxygen, but the calculated oxygen balance is less than - 200

Description of key information

non explosive

Key value for chemical safety assessment

Explosiveness:

non explosive

Additional information

EU Method A.14; Thermal sensitivity, Mechanical Sensitivity (Shock and Friction)

There are chemical groups associated with explosive properties. A screening test shows an endothermic effect (melting, 84.5 °C) and a decomposition of the substance in the range 290 - 440 °C with decomposition energy of 600 J/g. But the calculated oxygen balance is less than -200.

Furthermore no mechanical sensitivity (shock and friction) was observed.

Justification for classification or non-classification

The available data on explosivity of the test substance do not meet the criteria for classification according to Regulation (EC) 1272/2008 and are therefore conclusive but not sufficient for classification: There are chemical groups associated with explosive properties, but based on the calculated oxygen balance (less than -200) the substance is considered to be not explosive.