Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Unknown
Author:
Moreno, OM
Year:
1977
Bibliographic source:
Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81

Materials and methods

Principles of method if other than guideline:
No information is available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Pentane-2,3-dione
EC Number:
209-984-8
EC Name:
Pentane-2,3-dione
Cas Number:
600-14-6
Molecular formula:
C5H8O2
IUPAC Name:
pentane-2,3-dione
Test material form:
liquid
Specific details on test material used for the study:
No informaton provided

Test animals

Species:
rat
Details on test animals or test system and environmental conditions:
No informaton provided

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Details on oral exposure:
No informaton provided
Doses:
No informaton provided
No. of animals per sex per dose:
No informaton provided
Details on study design:
No informaton provided
Statistics:
No informaton provided

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
3 000 mg/kg bw
Based on:
not specified
Mortality:
No informaton provided
Clinical signs:
other: No informaton provided
Gross pathology:
No informaton provided

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
An LD50 of 3000 mg/kg bw in rats following oral exposure was reported. No further information available
Executive summary:

An LD50 of 3000 mg/kg bw in rats was reported. No further information is available.