Bis[2-(diethylamino)ethyl] adipate

Melting point / freezing point

Administrative data

Endpoint:

melting point/freezing point

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Materials and methods

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Bis[2-(diethylamino)ethyl] adipate

EC Number:

240-610-6

EC Name:

Bis[2-(diethylamino)ethyl] adipate

Cas Number:

16545-00-9

Molecular formula:

C18H36N2O4

IUPAC Name:

1,6-bis[2-(diethylamino)ethyl] hexanedioate

impurity 1

Reference substance name:

2-diethylaminoethanol

EC Number:

202-845-2

EC Name:

2-diethylaminoethanol

Cas Number:

100-37-8

Molecular formula:

C6H15NO

IUPAC Name:

2-(diethylamino)ethanol

Test material form:

liquid

Results and discussion

Any other information on results incl. tables

After evaluation the following values were recorded:

Table 8.1‑a      Values Pre-Test

Room Temperature	3.8°C	-20.8°C	-80°C
yellow-brown liquid	liquid, like at room temperature	liquid, like at room temperature	very viscous liquid (checked with a piece of wire)

After storage at -80 °C the test item was tempered to room temperature, the appearance and physical state were the same as in original test item.

The sponsor was consulted, according to REGULATION (EC) No 1907/2006 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL, Annex VII, dated 18. December 2006, the determination of the melting- / freezing point does not need to be conducted below a lower limit of - 20 °C.

Therefore no main test was performed.

Applicant's summary and conclusion

Conclusions:

In a pre-test, the test item Bis[2-(diethylamino)ethyl]adipate was still not solid at – 80°C. According to REGULATION (EC) No 1907/2006 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL, Annex VII, dated 18. December 2006, the determination of the melting- / freezing point does not need to be conducted below a lower limit of - 20 °C.
Therefore, no additional test was conducted and the melting point is stated as:
< - 80 °C (< 193.15 K).
No observations were made which might cause doubts on the validity of the study out-come. Therefore, the result of the study is considered valid

Executive summary:

In a pre-test, the test itemBis[2-(diethylamino)ethyl]adipatewas still not solid at – 80°C.According to REGULATION (EC) No 1907/2006 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL, Annex VII, dated 18. December 2006, the determination of the melting- / freezing point does not need to be conducted below a lower limit of - 20 °C.

Therefore, after consulting with the sponsor no additional test was conducted and the melting point is stated as:

< - 80 °C (< 193.15 K).