Registration Dossier
Registration Dossier
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EC number: 276-115-7 | CAS number: 71873-39-7
Endpoint summary
Administrative data
Description of key information
Not skin sensitising
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
There are no information about the skin sensititation potential of Acid Red 336, thus the available data on structural analogous Similar Substance 03 have been taken into account (details and explanations are included in the report attached to the IUCLID section 13).
Testing for the sensitizing properties of Similar Substance 03 was performed in female guinea pigs according to the method of Burhelr, according to the OECD guideline 406. Dermal induction was performed using 100 % test item moistened with deionized water. The control group was exposed to deionized water only. Challenge treatment was carried out with 20 % test item in deionized water.
No signs of irritation were observed in the control and the treatment group 24 and 48 hours after removal of the occlusive bandage. Based on the results of the study, the substance showed no evidence for sensitizing properties.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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