Registration Dossier
Registration Dossier
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EC number: 309-831-6 | CAS number: 101227-08-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Due to the structural similarities and consistent trend in toxicokinetic and (eco)toxicological behaviour, the selected source substances are considered suitable and systemic human health effects and ecotoxicological effects can be directly read-across in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5.
- Reason / purpose for cross-reference:
- read-across source
- GLP compliance:
- no
- Vehicle:
- no
- Total exposure duration:
- 96
- Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- No mortality and abnormalities were observed in the control and any treatment.
- Sublethal observations / clinical signs:
Table 1: Mortality of fish in %:
Nominal Concentration [mg/L]
Incubation time [h]
0
6
24
48
72
96
0
0
0
0
0
0
0
1000
0
0
0
0
0
0
3000
0
0
0
0
0
0
10000
0
0
0
0
0
0
- Validity criteria fulfilled:
- yes
- Conclusions:
- A semistatic acute fish test according to OECD 203 on the read-across substance Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters was conducted. The LC50 after 96 h was > 10000 mg/L.
- Executive summary:
A semistatic acute fish test according to OECD 203 on the read-across substance Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters was conducted. The LC50 after 96 h was > 10000 mg/L.
Reference
Description of key information
A semistatic acute fish test according to OECD 203 on the source substance Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters was conducted. The LC50 after 96 h was > 10000 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 10 000 mg/L
Additional information
A semistatic acute fish test according to OECD 203 on the source substance Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters was conducted. The LC50 after 96 h was > 10000 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
