Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
GLP compliance:
no
Test type:
acute toxic class method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-[2-[4-(2-benzoxazoleyl)phenyl]vinyl]benzoic acid
EC Number:
225-303-7
EC Name:
4-[2-[4-(2-benzoxazoleyl)phenyl]vinyl]benzoic acid
Cas Number:
4763-79-5
Molecular formula:
C22H15NO3
IUPAC Name:
4-[2-[4-(2-benzoxazoleyl)phenyl]vinyl]benzoic acid
Test material form:
solid: particulate/powder
Details on test material:
sample no. 0808024164

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
polyethylene glycol

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The median lethal dose of BENZOXAZOLSTILBENCARBONSAURE after single oral
administration to rats of both sexes, observed over a period of 14 days is:
LD5o (RAT): GREATER THAN 2000 MG/KG BODY WEIGHT