Registration Dossier
Registration Dossier
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EC number: 700-093-4 | CAS number: 176969-34-9
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid
- EC Number:
- 700-093-4
- Cas Number:
- 176969-34-9
- Molecular formula:
- C6H6F2N2O2
- IUPAC Name:
- 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficientopen allclose all
- Type:
- Pow
- Partition coefficient:
- 3.1
- Temp.:
- 23 °C
- pH:
- 3.5
- Remarks on result:
- other: final pH in distilled water
- Type:
- log Pow
- Partition coefficient:
- 0.5
- Temp.:
- 23 °C
- pH:
- 3.5
- Remarks on result:
- other: final pH in distilled water
- Type:
- Pow
- Partition coefficient:
- 0.006
- Temp.:
- 23 °C
- pH:
- 7.1
- Remarks on result:
- other: final pH in pH 7 buffer media
- Type:
- log Pow
- Partition coefficient:
- -2.2
- Temp.:
- 23 °C
- pH:
- 7.1
- Remarks on result:
- other: final pH in pH 7 buffer media
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
