Registration Dossier
Registration Dossier
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EC number: 204-255-0 | CAS number: 118-48-9
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Basic data are given
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 970
Materials and methods
- Type of study / information:
- Skin irritation with eight male subjects.
- Endpoint addressed:
- skin irritation / corrosion
- Principles of method if other than guideline:
- Skin irritation with eight male subjects.
- GLP compliance:
- no
- Remarks:
- pre-GLP study
Test material
- Reference substance name:
- 4H-3,1-benzoxazine-2,4(1H)-dione
- EC Number:
- 204-255-0
- EC Name:
- 4H-3,1-benzoxazine-2,4(1H)-dione
- Cas Number:
- 118-48-9
- Molecular formula:
- C8H5NO3
- IUPAC Name:
- 4H-3,1-benzoxazine-2,4(1H)-dione
- Details on test material:
- Isatoic acid, technical grade; no further data
Constituent 1
Method
- Ethical approval:
- not specified
Results and discussion
- Results:
- Application of the unchanged test substance to the forearm skin of volunteers for 24 hours under semiocclusive conditions did not produce any sign of irritation.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
