Propan-2-yl N-[(S)-(pentafluorophenoxy)(phenoxy) phosphoryl]-L-alaninate

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

01 November 2012-17 January 2013

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2013

Report date:

2013

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

Propan-2-yl N-[(S)-(pentafluorophenoxy)(phenoxy)-phosphoryl]-L-alanine

EC Number:

695-076-0

Cas Number:

1334513-02-8

Molecular formula:

C18H17F5NO5P

IUPAC Name:

Propan-2-yl N-[(S)-(pentafluorophenoxy)(phenoxy)-phosphoryl]-L-alanine

Test material form:

solid: particulate/powder

Remarks:

migrated information: powder

Details on test material:

- Name of test material (as cited in study report): GS-606962
- Substance type: organic
- Physical state: white powder
- Lot/batch No.: PSI-172(2)-1-1-12001
- Storage condition of test material: room temperature in the dark

Results and discussion

Boiling point

Boiling pt.:

ca. 290 °C

Atm. press.:

101.5 kPa

Any other information on results incl. tables

The thermographic data for Determinations 1 and 2 are in the following tables:

Table 2 Termographic Data -Determination 1

Thermal Events	Interpretation	Temperature
		°C	K
Endotherm	Melting Temperature	289.75	563

Atmospheric pressure: 101.5 kPa

Reduction in sample mass during heating: 0.0028g

Table 3 Termographic Data -Determination 2

Thermal Events	Interpretation	Temperature
		°C	K
Endotherm	Melting Temperature	289.90	563

Atmospheric pressure: 101.5 kPa

Reduction in sample mass during heating: 0.0032g

Mean boiling temperature: 290 ± 0.5°C (563±0.5 K)

Discussion: observation of the residue after heating showed a black stain remaining. As the loss of mass during the experiment did not account for all of the sample weight, this is most likely due to non volatile impurities in the test item. Also, as there was also some staining around the perforation on the outside of the crucible, this may indicate that there was some decomposition of the test item during boiling.

as the endotherm for melting was relatively wide in both determinations the result has been reported as a range from the onset to the endset of the peak.

Applicant's summary and conclusion

Conclusions:

The boiling temperature of the test item has been determined to be 290 ± 0.5°C (563±0.5 K) at 101.5 kPa.

Executive summary:

Boiling Temperature

290 ± 0.5°C (563±0.5 K) at 101.5 kPa by differential scanning calorimetry, designed to be compatible with Method A.2 (Boiling Temperature) of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.