Registration Dossier
Registration Dossier
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EC number: 616-644-6 | CAS number: 78629-20-6
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a (Q)SAR model, with limited documentation / justification
- Justification for type of information:
- QSAR prediction
Data source
Reference
- Reference Type:
- other: Predicted data
- Title:
- Unnamed
- Year:
- 2 015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 6,6-dimethylhept-1-en-4-yn-3-ol
- EC Number:
- 616-644-6
- Cas Number:
- 78629-20-6
- Molecular formula:
- C9H14O
- IUPAC Name:
- 6,6-dimethylhept-1-en-4-yn-3-ol
- Test material form:
- liquid
- Details on test material:
- Test item: enynolCAS No.: 78629-20-6Batch number: L62042NPhysical state: colourless liquidStorage: store it in a cool, dry, well-ventillated place, free from direct sunlight
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- other:
- Basis:
- other: (Q)SAR predition
- Remarks on result:
- positive indication of irritation
Any other information on results incl. tables
| Software | Method | Alert | Predicted value |
| ChemProp | Eye irritation and corrosion | Structural Alerts were found. | Eye irritation (H 315 with H 318 and H 314) |
Applicant's summary and conclusion
- Interpretation of results:
- Category 2B (mildly irritating to eyes) based on GHS criteria
- Conclusions:
- According to (Q)SAR modell: ChemProp, the predicted value indicated that enynol is irritating. The result meets the requirement of Hazard Category 2B.
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