Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1974
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: internal SOP Method B-10
- Deviations:
- not specified
- Principles of method if other than guideline:
- None
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- not specified
- Test organisms (species):
- activated sludge
- Details on inoculum:
- Active sewage sludge or activated sludge:
This is taken from the aerated compartment of an Husmann apparatus and has to be prepared freshly on a weekly basis. - Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 12 h
- Remarks on exposure duration:
- exposure duration 12-24 hours
- Post exposure observation period:
- Not applicable.
- Test temperature:
- 25 ± 2 °C
- Dissolved oxygen:
- Not applicable
- Salinity:
- Not applicable
- Nominal and measured concentrations:
- Not specified
- Details on test conditions:
- See part "Any other information on materials and methods incl. tables".
- Reference substance (positive control):
- no
- Duration:
- 12 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 300 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: exposure duration 12-24 hours
- Results with reference substance (positive control):
- Not applicable
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The IC50 for FAT 40069/A was found to be greater than 300 mg/L.
- Executive summary:
A key toxicity study of FAT 40069/A to activated sludge was determined in a 3-hours respiration inhibition test according to the internal SOP "Method B-10". The IC50 (3 h) of the test substance FAT 40069/A is greater than 300 mg/L.
Reference
Description of key information
The IC50 for FAT 40069/A was found to be greater than 300 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 300 mg/L
Additional information
A toxicity study of FAT 40069/A to activated sludge was conducted in a 3-hours respiration inhibition test according to the internal SOP Method B-10. The IC50 (3 h) of the test substance FAT 40069/A is 300 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
