Registration Dossier
Registration Dossier
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EC number: 231-177-4 | CAS number: 7440-69-9
Endpoint summary
Administrative data
Description of key information
2-year dietary exposure to 1400 (females) and 1750 (males) mg/kg bw was tolerated well (Preussmann 1985). The doses exceed the limit dose required for subacute and subchrnonic toxicity testing.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
- Study duration:
- subacute
- Species:
- rat
Additional information
Justification for classification or non-classification
A valid study for subacute oral toxicity in rats is available. No adverse effects were observed at the limit dose of 1000 mg/kg bw. Therefore, no GHS classification is needed.
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