Registration Dossier
Registration Dossier
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EC number: 232-391-0 | CAS number: 8013-07-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 24 hour static, acute toxicity study was performed according to the OECD guideline 202 (1984). Daphnia magnawere exposed for 24 hours to nominal concentrations of TK 11278. Based on nominal exposure concentrations the 24 hour EC50 was observed to be >100 mg/L (the highest concentration tested), the corresponding no-observed effect concentration (NOEC) was 100 mg/L.
A 24 hour static, tolerance study was conducted withArtemia salinaas part of a research project. Artemia salinawere exposed for 24 hours to the following nominal concentrations of epodixised soybean oil: 100, 1000 and 10000 mg/L. Based on nominal exposure concentrations the 24 hour TLm (median tolerance limit) was calculated to be 240 mg/L (Price et al).
Key value for chemical safety assessment
Additional information
A 24 hour static, acute toxicity study was performed according to the OECD guideline 202 (1984). Daphnia magna were exposed for 24 hours to nominal concentrations of TK 11278. Based on nominal exposure concentrations the 24 hour EC50 was observed to be >100 mg/L (the highest concentration tested), the corresponding no-observed effect concentration (NOEC) was 100 mg/L.
A 24 hour static, tolerance study was conducted withArtemia salinaas part of a research project. Artemia salina were exposed for 24 hours to the following nominal concentrations of epodixised soybean oil: 100, 1000 and 10000 mg/L. Based on nominal exposure concentrations the 24 hour TLm (median tolerance limit) was calculated to be 240 mg/L (Price et al).
The water solubility of ESBO is estimated to be <0.02 µg/L, categorised as insoluble REACH, see section 4.8 for details. Ideally aquatic toxicity studies should not be conducted above the limit of water solubility, the studies reported here tested nominal concentrations up to 10000 mg/L. According to Annex VII a short-term test on invertebrates is required unless there are mitigating factors such as the test substance is insoluble, this is the case for ESBO. Therefore, the invertebrate studies are reported here for information only (this study was also reported in the OECD SIDS Initial Assessment Report for SIAM 22, 18 -21 April 2006), the endpoints will not be used for PNEC setting or in any risk assessment.
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