Registration Dossier
Registration Dossier
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EC number: 205-391-3 | CAS number: 140-01-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
When rainbow trout (O. mykiss) were exposed to pentapotassium salt of DTPA, the 96-hour LC50 was > 1,000 mg/L, which is equivalent to 854 mg/L pentasodium DTPA (Na5DTPA).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 854 mg/L
Additional information
Two acute freshwater fish studies were assessed for this endpoint. One study was conducted with rainbow trout (Oncorhynchus mykiss) exposed to the pentapotassium salt of DTPA, while the other study was conducted with bluegill sunfish (Lepomis machrochirus) exposed to the pentasodium salt of DTPA. Upon contact with water, these DTPA salts are expected to dissociate, thus, these test chemicals are considered essentially equivalent in aquatic environments. Both studies were found to be of good quality and were comparable to or equivalent to guideline studies. The acute test with the rainbow trout was a limit test that concluded that the 96 hour LC50 for pentapotassium DTPA was >1,000 mg/L, which is equivalent to 854 mg/L pentasodium DTPA following stoichiometric conversion. The acute test with the bluegill sunfish concluded that the 96 -hour LC50 for pentasodium DTPA was 1115 mg/L. Since these toxicity results were conducted with two different fish species, the lower of the two values (854 mg/L) was selected as the key parameter for this endpoint.
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