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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
not reported
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: The data is taken from an abstract of an internal company report with incomplete reporting on the method; it is not possible to assess the accuracy of the information presented.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1980
Report date:
1980

Materials and methods

Principles of method if other than guideline:
Mice were exposed to 250, 500, 1000 or 2000 test material intraperitoneally. Ten mice were treated per dose level and the rate of mortality was recorded.
GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-methyl-3-decen-5-ol
EC Number:
279-815-0
EC Name:
4-methyl-3-decen-5-ol
Cas Number:
81782-77-6
Molecular formula:
C11H22O
IUPAC Name:
4-methyldec-3-en-5-ol
Test material form:
liquid

Test animals

Species:
mouse
Strain:
not specified
Sex:
male/female
Details on test animals or test system and environmental conditions:
TEST ANIMALS- Weight at study initiation: 17-22g

Administration / exposure

Route of administration:
intraperitoneal
Doses:
250, 500, 1000 and 2000
No. of animals per sex per dose:
10 animals per dose
Control animals:
not specified

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LC50
Effect level:
> 1 000 - < 2 000
Based on:
test mat.
Remarks on result:
other: units have not been reported
Mortality:
10/10 animals died at the highest dose administered 2000.No mortalities were recorded at any other dose.

Any other information on results incl. tables

No further information on results are available.

Applicant's summary and conclusion

Conclusions:
The LC50 of the test material was recorded to be 1000-2000 in mice, no units have been given.
Executive summary:

In a non GLP compliant study the acute toxicity of the test material was determined by intraperitoneal injection in mice at the following dose levels; 250, 500, 1000 and 2000. Ten mice were exposed per dose and the rate of mortality was recorded. The LC₅₀ was determined to be between 1000 - 2000, the units have not been recorded.