Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
other: QSAR model
Title:
VEGA in silico platform
Year:
2022
Bibliographic source:
Acute Toxicity (LD50) model (KNN) - v.1.0.0

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl mercaptoacetate
EC Number:
210-800-3
EC Name:
Ethyl mercaptoacetate
Cas Number:
623-51-8
Molecular formula:
C4H8O2S
IUPAC Name:
ethyl 2-sulfanylacetate

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
178 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Category 3 based on GHS criteria
Conclusions:
Under the test conditions, a LD50 of 178 mg/kg bw was obtained.