Registration Dossier
Registration Dossier
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EC number: 222-158-1 | CAS number: 3373-59-9
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2013-03-19 to 2013-11-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study performed in accordance with recognized test guideline
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Principles of method if other than guideline:
- NA
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
Test material
- Reference substance name:
- Methyl L-threoninate
- EC Number:
- 222-158-1
- EC Name:
- Methyl L-threoninate
- Cas Number:
- 3373-59-9
- Molecular formula:
- C5H11NO3
- IUPAC Name:
- Methyl (2S,3R)-2-amino-3-hydroxy-butanoate
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): L-threonine methyl ester
- Physical state: white crystalline powder
- Analytical purity: 99.8%
- Lot/batch No.: X5UYC99
- Expiration date of the lot/batch: July 2014
- Storage condition of test material: Frozen
Constituent 1
Results and discussion
Vapour pressure
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- ca. 1.2 Pa
- Remarks on result:
- other: The runs yielded a mean vapour pressure value at 25ºC of 1.2 Pa.
Any other information on results incl. tables
The results of the two runs:
| Run 1 | Run 2 | |
| Correlation (r): | -0.9994 | -0.9997 |
| Slope: | - 5488 | -5226 |
| Intercept: | 18.45 | 17.61 |
| Vp (Pa) at 25°C: | 1.12 | 1.21 |
The runs yielded a mean vapour pressure value at 25ºC of 1.2 Pa.
Applicant's summary and conclusion
- Conclusions:
- L-TME was found to have a vapour pressure of 1.2 Pa at 25°C.
- Executive summary:
The vapour pressure of L-TME was measured in accordance to OECD 104 and was found to be 1.2 Pa at 25°C
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