Myo-Inositol, hexakis(dihydrogen phosphate), sodium salt

Density

Link to relevant study record(s)

Reference

Endpoint:

density, other

Remarks:

Density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23.10.2017 - 26.10.2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study was performed in accordance with GLP requirements and no deviations were observed.

Justification for type of information:

Guideline study as required by REACH regulation 1907/2006

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Version / remarks:

• OECD Guidelines for the Testing of Chemicals, Method No. 109, adopted 02. Oct. 2012: “Density of Liquids and Solids “

Deviations:

not specified

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Version / remarks:

• Council Regulation (EC) No 440/2008 from 30 May 2008, published on 31. May 2008, Method A.3: “Relative Density”

Deviations:

not specified

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Key result

Type:

density

Density:

>= 2.039 - <= 2.041 g/cm³

Temp.:

20 °C

Remarks on result:

other: n=2 measurements, Standard deviation is: 0.0116 g/cm³

Results of the single determinations with the respective error as well as the mean value

and its standard deviation are presented in the following tables:

Determination	Density in g/cm3	Error of Determ. in g/cm^3
1	2.0483	0.0009
2	2.0319	0.0009

Parameter	Value	Unit	Standard Deviation	Relative Standard Deviation
Volume of Pycnometer	25.59	cm3	0.0006	0.00%
Density of Test Item	2.0401	g/cm3	0.0116	0.57%
Density of Test Item	2040.1	kg/m3	11.6	0.57%
Relative Density of Test Item	2.0401		0.0116	0.57%

Conclusions:

The density of the test item was calculated as 2.0401 ± 0.0009 g/cm³ at 20.0 ± 0.2°C

Executive summary:

According to OECD 109, using the pycnometer method, a density of 2.0401 ± 0.0009 g/cm³ at 20.0 ± 0.2°C was measured.

This value is the mean of two independent determinations with the maximum error of a single determination.

Standard deviation was 0.0116 g/cm³, showing good correlation of the two determinations.

Therefore, the study is considered valid.

The relative density of the test item has the same number value, but no unit, assuming that relative density is given as the ratio of test item density to density of water at 4°C, having a standard density of 0.999975

g/cm³ (source: CRC Handbook of Chemistry and Pyhsics - 90th edition / Section 6 - Fluid properties - p.6 -7).

Description of key information

Density: 2.0401 +/- 0.0009 g/cm3 at 20°C +/- 0.2°C (Method OECD 109;  respectively to EC Guideline EU A.3; pycnometer method)

Key value for chemical safety assessment

Relative density at 20C:

2.04

Additional information

The density of the substance, determinded by pycnomter method, was calculated as 2.0401 ± 0.0009 g/cm3 at 20.0 ± 0.2°C.

This value is the mean of two independent determinations with the maximum error of a single determination.

Standard deviation was 0.0116 g/cm3, showing good correlation of the two determinations.

The relative density of the test item has the same number value, but no unit, assuming that relative density is given as the ratio of test item density to density of water at 4°C, having a standard density of 0.999975 g/cm³ (source: CRC Handbook of Chemistry and Pyhsics - 90th edition / Section 6 - Fluid properties - p.6 -7).