Registration Dossier
Registration Dossier
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EC number: 611-575-8 | CAS number: 577953-88-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
One key study was completed according to a OECD 301B Ready Biodegradation Carbon Dioxide (C02) Evolution Test (Modified Sturm Test) of Montelukast Dicyclohexylamine salt.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
The test material attained 3 and 7% degradation (bottle A and B respectively) after 28 days and therefore cannot be considered to be readily biodegradable under the strict terms and conditions of OECD Guideline No 301B.
The relative biodegradation values calculated from the measurements performed during the test period revealed no significant biodegradation of Montelukast dicyclohexylamine salt.
In the toxicity control, Montelukast dicyclohexylamine salt was found not to inhibit microbial activity. Since all criteria for acceptability of the test were met, this study was considered to be valid.
In conclusion, Montelukast dicyclohexylamine salt was designated as not readily biodegradable.
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