Registration Dossier
Registration Dossier
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EC number: 231-995-1 | CAS number: 7783-40-6
Endpoint summary
Administrative data
Description of key information
The environmental hazard assessment was conducted based on the available data of the registered substance. The following key information from aquatic invertebrates, fish, algae and microorganisms studies have been used to evaluate the aquatic toxicity of the target substance:
Toxicity to algae (Desmodesmus subspicatus): 72-h EC50: >100 mg/l (growth rate); 72 -h EC50: >100 mg/l (growth rate) (OECD 201, GLP)
Toxicity to invertebrates (Daphnia Magna): 48h NOEC: >100 mg/l (mortality); 48h EC50: >100 mg/l (mortality), 48h LOEC: >100 mg/l (mortality); (OECD 202, GLP)
Toxicity to fish (Danio rerio): 96 NOEC ≥100 mg/l (mortality); 96h LC50 >100 mg/l (mortality); 96h LOEC >100 mg/l (OECD 203, GLP)
Toxicity to microorganisms (activated sludge respiration inhibition) : IC50 149 mg/l (similar or equivalent to OECD 209). Note: RA substance (Sodium fluoride)
Magnesium fluoride is an inorganic substance moderate soluble in water (76 mg/l) and it will partially be dissociated form in an aqueous solution. Based on the study results on daphnids, fish and algae determined for the registered substance, no toxicity occurred up to the maximum test concentrations of >100 mg/l (daphnids), >100 mg/l (fish) and >100 mg/l (algae). The results were based on nominal test concentrations.
No reliable long-term studies are available for aquatic invertebrates, fish and algae.
PNEC values were derived from studies conducted with the test substance in accordance with the “Guidance on information requirements and chemical safety assessment, Chapter R.10”.
Additional information
Study results of the read across substance sodium fluoride have been provided and used as supporting information for the environmental hazard assessment. The read-across rationale can be found in the category approach document attached in Section 13 of IUCLID and is fully incorporated in the CSR.
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