Registration Dossier
Registration Dossier
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EC number: 460-110-3 | CAS number: 797751-43-0 WASOX-MMAC2
Endpoint summary
Administrative data
Description of key information
Additional information
Data waiving (study technically not feasible): The study is technically not feasible since the substance is hydrolytically unstable (half-life < 1h). The Log Koc and Koc of test item should be understood based on its degradation products since it undergoes rapid hydrolysis (half-life < 1h) in water to acetone oxime (log Kow = 1.783 and Koc = 60.7, KOCWIN v2.00) and silanols (Log Kow in the range of 1.642-2.227 and Koc 43.89-168.6 KOWWIN v1.68). Morevoer, it should be pointed out that the corresponding silanols undergo continuous condensation reactions to produce higher molecular weight siloxanes which are considered biologically unavailable. Therefore, the Key value for chemical safety assessment would be the adsorption coefficient of acetone oxime.
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